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Article

Linker Domains: Why ABC Transporters 'Live in Fragments no Longer'.

Trends in biochemical sciences - 1 Feb 2020

Ford Robert C, Marshall-Sabey Dominic, Schuetz John

Abstract excerpt

ATP-binding cassette (ABC) transporters are membrane proteins present in all kingdoms of life. We have considered the disordered region that connects the N- and C-terminal halves in many eukaryotic ABC transporters, allowing all four consensus functional domains to be linked. The recent availability of structures of ABC transporters containing linker regions has allowed us to identify the start and end points of...

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Identifiers

PMID: 31839525
DOI: 10.1016/j.tibs.2019.11.004
PMCID: PMC7219603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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