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Evolutionary history of ATP‐binding cassette proteins

4 Nov 2020

Abstract excerpt

ATP-binding cassette (ABC) proteins are found in every sequenced genome and evolved deep in the phylogenetic tree of life. ABC proteins form one of the largest homologous protein families, with most being involved in substrate transport across biological membranes, and a few cytoplasmic members regulating in essential processes like translation. The predominant ABC protein classification scheme is derived from...

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PMID: 33145769
DOI: 10.1002/1873-3468.13985

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