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Article

The multidrug transporter Pdr5 on the 25th anniversary of its discovery: an important model for the study of asymmetric ABC transporters.

The Biochemical journal - 1 May 2015

Golin John, Ambudkar Suresh V

Abstract excerpt

Asymmetric ABC (ATP-binding cassette) transporters make up a significant proportion of this important superfamily of integral membrane proteins. These proteins contain one canonical (catalytic) ATP-binding site and a second atypical site with little enzymatic capability. The baker's yeast (Saccharomyces cerevisiae) Pdr5 multidrug transporter is the founding member of the Pdr subfamily of asymmetric ABC...

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Share to Adenosine Triphosphatases
Share to ATP-Binding Cassette Transporters

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Multiple

Share to Fungal Proteins

Share to Membrane Transport Proteins

Share to Protein Interaction Domains and Motifs

Share to Protein Structure, Secondary

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Source

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Identifiers

PMID: 25886173
DOI: 10.1042/BJ20150042
PMCID: PMC4784962

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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