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Article

Increased DNA methylation in the spermatogenesis‐associated (SPATA) genes correlates with infertility

15 Dec 2019

Abstract excerpt

BACKGROUND: Spermatogenesis-associated (SPATA) family of genes plays important roles in spermatogenesis, sperm maturation or fertilization. The knockout studies in mice have demonstrated that SPATA genes are crucial for fertility. Gene expression and genetic polymorphism studies have further suggested their correlation with infertility; however, methylation analysis of SPATA genes in human male infertility has...

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Share to Epigenetics and DNA Methylation
Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 31838782
DOI: 10.1111/andr.12742

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