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Article

Homozygous mutation in SPATA16 is associated with male infertility in human globozoospermia.

American journal of human genetics - 1 Oct 2007

Dam Anika H D M, Koscinski Isabelle, Kremer Jan A M, Moutou Celine, Jaeger Anne-Sophie, Oudakker Astrid R, Tournaye Herman, Charlet Nicolas, Lagier-Tourenne Clotilde, van Bokhoven Hans, Viville Stephane

Abstract excerpt

Globozoospermia is a rare (incidence <0.1% in male infertile patients) form of teratozoospermia, mainly characterized by round-headed spermatozoa that lack an acrosome. It originates from a disturbed spermiogenesis, which is expected to be induced by a genetic factor. Several family cases and rec...

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Source

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Identifiers

PMID: 17847006
DOI: 10.1086/521314
PMCID: PMC2227931

Genes

SPATA16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17847006-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Homozygous mutation in SPATA16 is associated with male infertility in human globozoospermia.PMID 17847006Read ↗

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