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Epigenetics of Male Infertility: The Role of DNA Methylation

22 Jul 2021

Abstract excerpt

In recent years, a number of studies focused on the role of epigenetics, including DNA methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the knowledge concerning the gene and genome methylation and its regulation during spermatogenesis, specifically in the context of male infertility etiopathogenesis. Overall, the findings support the hypothesis that sperm DNA methylation is...

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PMID: 34368137
DOI: 10.3389/fcell.2021.689624

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