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Genome-wide DNA methylation changes in human spermatogenesis

2023-11-01

Abstract excerpt

<h4>Summary</h4> Sperm production and function require the correct establishment of DNA methylation patterns in the germline. Here, we examined the genome-wide DNA methylation changes during human spermatogenesis and its alterations in disturbed spermatogenesis. We found that spermatogenesis is associated with remodeling of the methylome, comprising a global-decline in DNA methylation in primary spermatocytes fol...

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Identifiers and source

Literature Corpus work
f8959618-c260-5a7b-a626-8a4846bf5b17
DOI
10.1101/2023.10.27.564382
Open publication

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Genome-wide DNA methylation changes in human spermatogenesisDOI 10.1101/2023.10.27.564382
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