Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

dmrt1 Is Responsible for Androgen-Induced Masculinization in Nile Tilapia.

Genes - 23 Sept 2024

Dai Shengfei, Li Mei, Yuan Jie, Wei Xueyan, Ma Eryan, Wang Deshou, Li Minghui

Abstract excerpt

17α-Methyltestosterone (MT) is a widely used androgen for all-male fish production in aquaculture. However, the molecular mechanism underlying MT-induced masculinization remains unclear. In this study, we aim to identify the key gene responsible for MT-induced masculinization using the Nile tilapia (Oreochromis niloticus) amhy, dmrt1, and gsdf mutants, which exhibit male-to-female sex reversal. Nile tilapia fry...

Topics

Join the communities discussing this publication.

Androgens
Cichlids
Fish Proteins
Gene Expression Regulation, Developmental
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sex Differentiation

Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 39336829
DOI: 10.3390/genes15091238
PMCID: PMC11431369

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

dmrt1 Is Responsible for Androgen-Induced Masculinization in Nile Tilapia.PMID 39336829Read ↗

Steroid hormone-deprived sex reversal in cyp11a1 mutant XX tilapia experiences an ovary-like stage at molecular level.Semantic proximity Read ↗

Cyp17a1 is Required for Female Sex Determination and Male Fertility by Regulating Sex Steroid Biosynthesis in FishSemantic proximity Read ↗

Dmrt1 is the only male pathway gene tested indispensable for sex determination and functional testis development in tilapiaSemantic proximity Read ↗

Mutation of foxl2 or cyp19a1a Results in Female to Male Sex Reversal in XX Nile Tilapia.Semantic proximity Read ↗

Disruption of dmrt1 rescues the all-male phenotype of the cyp19a1a mutant in zebrafish - a novel insight into the roles of aromatase/estrogens in gonadal differentiation and early folliculogenesis.Semantic proximity Read ↗

<i>gsdf</i> is a downstream gene of <i>dmrt1</i> that functions in the male sex determination pathway of the Nile tilapiaSemantic proximity Read ↗

Dietary aromatase inhibitor treatment converts XY gsdf homozygous mutants to sub-fertile male in Nile tilapia (Oreochromis niloticus)Semantic proximity Read ↗

Mutation ofcyp19a1bresults in sterile males due to efferent duct obstruction in Nile tilapiaSemantic proximity Read ↗

Roles of anti-Müllerian hormone and its duplicates in sex determination and germ cell proliferation of Nile tilapiaSemantic proximity Read ↗

Doublesex- and Mab-3-Related Transcription Factor-1 Repression of Aromatase Transcription, a Possible Mechanism Favoring the Male Pathway in TilapiaSemantic proximity Read ↗

Effects of letrozole and 17α‐methyltestosterone on gonadal development in all‐female triploid rainbow trout ( Oncorhynchus mykiss )Semantic proximity Read ↗

Development and gene expression analysis of gonad during 17α-methyltestosterone-induced sex reversal in mandarin fish (Siniperca chuatsi)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.