Article
FAS -670 A/G polymorphism may be associated with the depletion of CD4(+) T lymphocytes in HIV-1 infection.
Human immunology - 1 Oct 2015
Hermes Renata Bezerra, Santana Bárbara Brasil, Lima Sandra Souza, Neris Martins Feitosa Rosimar, de Oliveira Guimarães Ishak Marluísa, Ishak Ricardo, Vallinoto Antonio Carlos Rosário
Abstract excerpt
In this study, the polymorphisms in the FAS and FASL genes was investigated in a sample of 198 HIV-1-seropositive individuals and 191 seronegative controls to evaluate a possible association between polymorphisms and the infection. The identification of the A and G alleles of the FAS -670 polymorphism was accomplished through polymerase chain reaction assays followed by digestion with the restriction enzyme MvaI....
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