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Article

Complement Receptor 1 (CR1, CD35) Polymorphisms and Soluble CR1: A Proposed Anti-inflammatory Role to Quench the Fire of "Fogo Selvagem" Pemphigus Foliaceus.

Frontiers in immunology - 1 Jan 2019

Oliveira Luana Caroline, Kretzschmar Gabriela Canalli, Dos Santos Andressa Cristina Moraes, Camargo Carolina Maciel, Nisihara Renato Mitsunori, Farias Ticiana Della Justina, Franke Andre, Wittig Michael, Schmidt Enno, Busch Hauke, Petzl-Erler Maria Luiza, Boldt Angelica Beate Winter

Abstract excerpt

Pemphigus foliaceus is an autoimmune disease that is sporadic around the world but endemic in Brazil, where it is known as fogo selvagem (FS). Characterized by autoantibodies against the desmosomal cadherin desmoglein 1, FS causes painful erosions, and crusts that may be widespread. The recognition of antigens, including exposed sugar moieties, activates the complement system. Complement receptor 1 (CR1, CD35),...

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Identifiers

PMID: 31824479
DOI: 10.3389/fimmu.2019.02585
PMCID: PMC6883348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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