Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dissecting the associations of endemic pemphigus foliaceus (Fogo Selvagem) with HLA-DRB1 alleles and genotypes.

Genes and immunity - 1 Mar 2003

Pavoni D P, Roxo V M M S, Marquart Filho A, Petzl-Erler M L

Abstract excerpt

Endemic pemphigus foliaceus (EPF) is a blistering skin disease characterized by autoantibodies against the desmosomal protein desmoglein 1. Genetic and environmental factors influence its pathogenesis. A total of 128 patients and 402 controls from an ethnically admixed Brazilian population were analyzed for associations by allele and genotype with HLA-DRB1. The alleles DRB1(*)0101, (*)0102, (*)0103, (*)0404,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Case-Control Studies
Share to Endemic Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Predisposition to Disease

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Share to Pemphigus

Source

Identifiers

PMID: 12618858
DOI: 10.1038/sj.gene.6363939

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dissecting the associations of endemic pemphigus foliaceus (Fogo Selvagem) with HLA-DRB1 alleles and genotypes.PMID 12618858Read ↗

Tunisian endemic pemphigus foliaceus is associated with the HLA-DR3 gene: anti-desmoglein 1 antibody-positive healthy subjects bear protective alleles.Semantic proximity Read ↗

Pemphigus foliaceus and desmoglein 1 gene polymorphism: is there any relationship?Semantic proximity Read ↗

Differential HLA class I and class II associations in pemphigus foliaceus and pemphigus vulgaris patients from a prevalent Southeastern Brazilian region.Semantic proximity Read ↗

Variation in genes implicated in B-cell development and antibody production affects susceptibility to pemphigus.Semantic proximity Read ↗

Epistasis between DSG1 and HLA class II genes in pemphigus foliaceus.Semantic proximity Read ↗

HLA class II polymorphism contributes to specify desmoglein derived peptides in pemphigus vulgaris and pemphigus foliaceus.Semantic proximity Read ↗

An epitope in the third hypervariable region of the DRB1 gene is involved in the susceptibility to endemic pemphigus foliaceus (fogo selvagem) in three different Brazilian populations.Semantic proximity Read ↗

Individual and epistatic effects of genetic polymorphisms of B-cell co-stimulatory molecules on susceptibility to pemphigus foliaceus.Semantic proximity Read ↗

Investigation of the predisposing factor of pemphigus and its clinical subtype through a genome-wide association and next generation sequence analysis.Semantic proximity Read ↗

Cytokine gene polymorphisms in endemic pemphigus foliaceus: a possible role for IL6 variants.Semantic proximity Read ↗

Beyond the HLA polymorphism: A complex pattern of genetic susceptibility to pemphigusSemantic proximity Read ↗

Polymorphism of the promoter region and exon 1 of the CTLA4 gene in endemic pemphigus foliaceus (fogo selvagem).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.