Article
Cell Culture Studies of the Efficacy and Barrier to Resistance of Sofosbuvir-Velpatasvir and Glecaprevir-Pibrentasvir against Hepatitis C Virus Genotypes 2a, 2b, and 2c.
Antimicrobial agents and chemotherapy - 21 Feb 2020
Ramirez Santseharay, Fernandez-Antunez Carlota, Mikkelsen Lotte S, Pedersen Jannie, Li Yi-Ping, Bukh Jens
Abstract excerpt
The introduction of highly efficient therapies with direct-acting antivirals (DAA) for patients with chronic hepatitis C virus (HCV) infection offers exceptional opportunities to globally control this deadly disease. For achieving this ambitious goal, it is essential to prevent antiviral resistance against the most optimal first-line and retreatment DAA choices. We performed independent comparisons of the...
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