Article
Evaluation of the relationship between IL-12, IL-13 and TNF-α gene polymorphisms with the susceptibility to brucellosis: a case control study.
BMC infectious diseases - 9 Dec 2019
Kazemi Sima, Vaisi-Raygani Asad, Keramat Fariba, Saidijam Massoud, Soltanian Ali Reza, Alahgholi-Hajibehzad Mahdi, Hashemi Seyed Hamid, Alikhani Mohammad Yousef
Abstract excerpt
BACKGROUND: The cytokine gene polymorphism is important for the genetic susceptibility of infectious diseases. The aim of the present study was to investigate the relationship between TNF-α, IL-12, and IL-13 gene polymorphisms and predisposition to brucellosis. METHODS: In this study, 107 patients with brucellosis and 107 healthy individuals were evaluated. The SNPs of TNF-α)- 238 G/A) and IL-12 (+ 1188 A/C) were...
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