Article
Polymorphism of cytokine and innate immunity genes associated with bovine brucellosis in cattle.
Molecular biology reports - 1 May 2014
Prakash Om, Kumar Amit, Sonwane Arvind, Rathore Rajesh, Singh Ran Vir, Chauhan Anuj, Kumar Pushpendra, Renjith R, Yadav Ramji, Bhaladhare Ashish, Baqir Mohd, Sharma Deepak
Abstract excerpt
Genetic susceptibility to brucellosis is multifactorial, and it is known that impairment of the immune system could contribute to risk for getting brucellosis. The aim of the study was to find association of bovine brucellosis with 20 SNPs pertaining to bovine cytokine (IFNG, IFNGR1, IFNGR2, TNFA) and innate immunity (SLC11A1, TLR1, TLR4, and TLR9) genes using PCR-RFLP genotyping technique and it was observed...
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