Analysis of IL-10 and IL-6 Gene Polymorphisms and Their Serum Levels in Patients with Brucellosis: A Case Control Study.

doi:10.3109/08820139.2015.1096285

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Article

Analysis of IL-10 and IL-6 Gene Polymorphisms and Their Serum Levels in Patients with Brucellosis: A Case Control Study.

Immunological investigations - 1 Jan 2016

Kazemi Sima, Saidijam Massoud, Hashemi Seyed Hamid, Karami Manoochehr, Vaisi-Raygani Asad, Alikhani Mohammad Yousef

Abstract excerpt

BACKGROUND: It seems that polymorphism in the regulatory areas of cytokine genes affects the cytokine production capacity and may play a role in the development of infectious diseases. Interleukin-10 (IL-10) and Interleukin-6 (IL-6), which are cytokines of Th2, cause the macrophage become inactive and patient conditions get worse. METHODS: In this case-control study, 60 patients with brucellosis and 60 healthy...

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PMID: 26849072
DOI: 10.3109/08820139.2015.1096285

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