Article
TNF-alpha, TGF-beta, IL-10, IL-6 and IFN-gamma gene polymorphisms as risk factors for brucellosis.
The new microbiologica - 1 Apr 2009
Karaoglan Ilkay, Pehlivan Sacide, Namiduru Mustafa, Pehlivan Mustafa, Kilinçarslan Can, Balkan Yasemin, Baydar Ibrahim
Abstract excerpt
Polymorphisms in the regulatory regions of cytokine genes can affect the level of cytokine production, and may be associated with predisposition to infectious diseases as well as different clinical outcomes. The aim of this study was to investigate the association of the polymorphisms of IL-6 (-174), IL-10 (-1082, -819), IFN gamma (+874), TGF beta (codon 10, codon 25) and TNF alpha (-308) genes with brucellosis...
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