Article
An analysis of mutational signatures of synonymous mutations across 15 cancer types.
BMC medical genetics - 9 Dec 2019
Bin Yannan, Wang Xiaojuan, Zhao Le, Wen Pengbo, Xia Junfeng
Abstract excerpt
BACKGROUND: Synonymous mutations have been identified to play important roles in cancer development, although they do not modify the protein sequences. However, relatively little research has specifically delineated the functionality of synonymous mutations in cancer. RESULTS: We investigated the nucleotide-based and amino acid-based features of synonymous mutations across 15 cancer types from The Cancer Genome...
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