Article
Association of Melatonin Pathway Gene's Single-Nucleotide Polymorphisms with Systemic Lupus Erythematosus in a Chinese Population.
Journal of immunology research - 1 Jan 2019
Wang Peng, Liu Lei, Zhao Li-Fang, Zhao Chan-Na, Mao Yan-Mei, Dan Yi-Lin, Wu Qian, Li Xiao-Mei, Wang De-Guang, Pan Hai-Feng
Abstract excerpt
OBJECTIVES: This study was to investigate the association of melatonin (MTN) pathway gene's single-nucleotide polymorphisms (SNPs) with susceptibility to systemic lupus erythematosus (SLE). METHODS: We recruited 495 SLE patients and 493 healthy controls, 11 tag SNPs in MTN receptor 1a (MTNR1a), MTNR1b, and arylalkylamine N-acetyltransferase (AANAT) genes were genotyped and analyzed. Serum MTN concentration was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
