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Melatonin pathway genes and breast cancer risk among Chinese women.

Breast cancer research and treatment - 1 Apr 2012

Deming Sandra L, Lu Wei, Beeghly-Fadiel Alicia, Zheng Ying, Cai Qiuyin, Long Jirong, Shu Xiao Ou, Gao Yu-Tang, Zheng Wei

Abstract excerpt

Previous studies suggest that melatonin may act on cancer growth through a variety of mechanisms, most notably by direct anti-proliferative effects on breast cancer cells and via interactions with the estrogen pathway. Three genes are largely responsible for mediating the downstream effects of melatonin: melatonin receptors 1a and 1b (MTNR1a and MTNR1b), and arylalkylamine N-acetyltransferase (AANAT). It is...

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Identifiers

PMID: 22138747
DOI: 10.1007/s10549-011-1884-5
PMCID: PMC3777385

Genes

AANAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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