Article
A genome-wide association study for melatonin secretion.
Scientific reports - 16 May 2022
Liu Pi-Hua, Chuang Gwo-Tsann, Hsiung Chia-Ni, Yang Wei-Shun, Ku Hsiao-Chia, Lin Yi-Ching, Chen Yi-Shun, Huang Yu-Yao, Lin Chia-Hung, Li Wen-Yi, Lin Jou-Wei, Hsu Chih-Neng, Hwang Juey-Jen, Liao Karen Chia-Wen, Hsieh Meng-Lun, Lee Hsiao-Lin, Shen Chen-Yang, Chang Yi-Cheng
Abstract excerpt
Melatonin exerts a wide range of effects among various tissues and organs. However, there is currently no study to investigate the genetic determinants of melatonin secretion. Here, we conducted a genome-wide association study (GWAS) for melatonin secretion using morning urine 6-hydroxymelatonin sulfate-to-creatinine ratio (UMCR). We initially enrolled 5000 participants from Taiwan Biobank in this study. After...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.