Article
Positive relationship between melatonin receptor type 1B polymorphism and rheumatoid factor in rheumatoid arthritis patients in the Korean population.
Journal of pineal research - 1 Sept 2005
Ha Eunyoung, Choe Bong-Keun, Jung Kyung Hee, Yoon Seo Hyun, Park Hae Jeong, Park Hun Kuk, Yim Sung-Vin, Chung Joo-Ho, Bae Hyun-Su, Nam Min, Baik Hyung Hwan, Hong Seung-Jae
Abstract excerpt
Melatonin is reported to be an anti-inflammatory agent. No genetic study concerning the association between melatonin and inflammatory disease has yet been reported. Here we performed a polymorphism study on the melatonin receptor type 1B (MTNR1B) in Korean rheumatoid arthritis (RA) patients and controls. The polymorphism of MTNR1B located in 3'-untranslated region (rs 1562444) was selected for its higher rate of...
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