Article
Associations of melatonin receptor gene polymorphisms with Graves' disease.
PloS one - 1 Jan 2017
Lin Jiunn-Diann, Yang Shun-Fa, Wang Yuan-Hung, Fang Wen-Fang, Lin Ying-Chin, Liou Bing-Chun, Lin Yuh-Feng, Tang Kam-Tsun, Cheng Chao-Wen
Abstract excerpt
BACKGROUND: Melatonin plays an important role in immunity and has been linked to autoimmune diseases. Possible associations of single-nucleotide polymorphisms (SNPs) of melatonin receptor type 1A (MTNR1A) and 1B (MTNR1B), with autoimmune thyroid disease in an ethnic Chinese (i.e., Taiwanese) population were examined. MATERIALS AND METHODS: Totally, 83 Hashimoto's thyroiditis patients, 319 Graves' disease (GD),...
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