Article
Additional common loci associated with stroke and obesity identified using pleiotropic analytical approach.
Molecular genetics and genomics : MGG - 1 Mar 2020
Wang Lianke, Xu Fei, Brickell Anna, Sun Nan, Mao Xiangjie, Zhang Qiang, Wang Ganyi, Zhou Qianyu, Yang Bin, Li Fangwei, Yue Limin, Zhang Weidong, Hao Yibin, Sun Changqing
Abstract excerpt
Stroke is a complex disease with multiple etiologies. Numerous studies suggest an established association between obesity and stroke, which may partly arise from the shared genetic components between the two phenotypes. Despite genome-wide association studies (GWASs) have identified some loci associated with stroke and obesity individually, the estimated genetic variability explained by these loci is limited...
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