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Article

Can genetic pleiotropy replicate common clinical constellations of cardiovascular disease and risk?

PloS one - 1 Jan 2012

Gottesman Omri, Drill Esther, Lotay Vaneet, Bottinger Erwin, Peter Inga

Abstract excerpt

The relationship between obesity, diabetes, hyperlipidemia, hypertension, kidney disease and cardiovascular disease (CVD) is established when looked at from a clinical, epidemiological or pathophysiological perspective. Yet, when viewed from a genetic perspective, there is comparatively little data synthesis that these conditions have an underlying relationship. We sought to investigate the overlap of genetic...

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Identifiers

PMID: 23029515
DOI: 10.1371/journal.pone.0046419
PMCID: PMC3460880

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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