Shared genetic etiology of hypertension and stroke: evidence from bioinformatics analysis of genome-wide association studies.

Abstract excerpt

Hypertension is the most significant modifiable risk factor for cerebrovascular disease. It has been estimated that about 54% of strokes worldwide can be attributed to hypertension. However, there has not been a systematic study assessing the shared genetic susceptibility to hypertension and stroke on a genome-wide level. In this study, SNPs associated with essential hypertension and stroke were collected from...

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