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Article

Identification of multi-omic pleiotropy factors for peripheral artery disease.

Human molecular genetics - 26 May 2026

Hu Jiaqi, Ochoa Chaar Cassius I, Zhao Hongyu, DeWan Andrew T

Abstract excerpt

BACKGROUND: Peripheral artery disease (PAD) is prevalent and frequently co-occurs with type 2 diabetes (T2D) and coronary artery disease (CAD). Although shared genetic factors-pleiotropy-may contribute to these comorbidities, few studies have examined pleiotropy at the transcriptomic and proteomic levels. METHODS: We generated summary statistics for transcriptome-wide (TWAS) and proteome-wide (PWAS) association...

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Identifiers

PMID: 42224455
DOI: 10.1093/hmg/ddag035

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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