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Article

The Transcription Factor FOXN1 Regulates Skin Adipogenesis and Affects Susceptibility to Diet-Induced Obesity.

The Journal of investigative dermatology - 1 Jun 2020

Walendzik Katarzyna, Kopcewicz Marta, Bukowska Joanna, Panasiewicz Grzegorz, Szafranska Bozena, Gawronska-Kozak Barbara

Abstract excerpt

FOXN1, a transcription factor expressed in the epidermis, regulates keratinocyte differentiation and participates in skin wound healing. In this study, we explored the impact of FOXN1 insufficiency on diet-stimulated weight gain and dermal white adipose tissue regulation in the intact and wounded skin of FOXN1eGFP/+ (heterozygotes, FOXN1-insufficient) mice in the context of age and diet. The results showed that...

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Identifiers

PMID: 31811821
DOI: 10.1016/j.jid.2019.11.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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