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Article

Noggin depletion in adipocytes promotes obesity in mice

10 Apr 2019

Abstract excerpt

Obesity has increased to pandemic levels and enhanced understanding of adipose regulation is required for new treatment strategies. Although bone morphogenetic proteins (BMPs) influence adipogenesis, the effect of BMP antagonists such as Noggin is largely unknown. The aim of the study was to define the role of Noggin, an extracellular BMP inhibitor, in adipogenesis. We generated adipose-derived progenitor cells...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 31027994
DOI: 10.1016/j.molmet.2019.04.004

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