Article
Changing in lipid profile induced by the mutation of Foxn1 gene: A lipidomic analysis of Nude mice skin.
Biochimie - 1 Nov 2015
Lanzini Justine, Dargère Delphine, Regazzetti Anne, Tebani Abdellah, Laprévote Olivier, Auzeil Nicolas
Abstract excerpt
Nude mice carry a spontaneous mutation affecting the gene Foxn1 mainly expressed in the epidermis. This gene is involved in several skin functions, especially in the proliferation and the differentiation of keratinocytes which are key cells of epithelial barrier. The skin, a protective barrier for the body, is essentially composed of lipids. Taking into account these factors, we conducted a lipidomic study to...
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