Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Equine Mx1 Restricts Influenza A Virus Replication by Targeting at Distinct Site of its Nucleoprotein.

Viruses - 2 Dec 2019

Fatima Urooj, Zhang Zhenyu, Zhang Haili, Wang Xue-Feng, Xu Ling, Chu Xiaoyu, Ji Shuang, Wang Xiaojun

Abstract excerpt

Interferon-mediated host factors myxovirus (Mx) proteins are key features in regulating influenza A virus (IAV) infections. Viral polymerases are essential for viral replication. The Mx1 protein has been known to interact with viral nucleoprotein (NP) and PB2, resulting in the influence of polymerase activity and providing interspecies restriction. The equine influenza virus has evolved as an independent lineage...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Horse Diseases
Share to Influenza A virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Influenza, Human

Share to Madin Darby Canine Kidney Cells

Share to Myxovirus Resistance Proteins

Share to Nucleocapsid Proteins

Share to Orthomyxoviridae Infections

Share to Viral Core Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 31810278
DOI: 10.3390/v11121114
PMCID: PMC6950424

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Equine Mx1 Restricts Influenza A Virus Replication by Targeting at Distinct Site of its Nucleoprotein.PMID 31810278Read ↗

Diversity of interferon inducible Mx gene in horses and association of variations with susceptibility vis-à-vis resistance against equine influenza infection.Semantic proximity Read ↗

The Nucleoprotein of Newly Emerged H7N9 Influenza A Virus Harbors a Unique Motif Conferring Resistance to Antiviral Human MxASemantic proximity Read ↗

Equine MX2 is a restriction factor of equine infectious anemia virus (EIAV).Semantic proximity Read ↗

Protective role of interferon-induced Mx GTPases against influenza virusesSemantic proximity Read ↗

Influenza A Virus Strains Differ in Sensitivity to the Antiviral Action of Mx-GTPaseSemantic proximity Read ↗

Mammalian Adaptation of an Avian Influenza A Virus Involves Stepwise Changes in NS1.Semantic proximity Read ↗

Deep mutational scanning identifies sites in influenza nucleoprotein that affect viral inhibition by MxA.Semantic proximity Read ↗

Deep Mutational Scanning Identifies Sites in Influenza Nucleoprotein That Affect Viral Inhibition by MxASemantic proximity Read ↗

Avian influenza A virus adaptation to the equine host and identification of host-specific markersSemantic proximity Read ↗

Replication Restriction of Influenza A(H5N1) Clade 2.3.4.4b Viruses by Human Immune Factor, 2023–2024Semantic proximity Read ↗

Pandemic influenza A viruses escape from restriction by human MxA through adaptive mutations in the nucleoprotein.Semantic proximity Read ↗

Mx genes: host determinants controlling influenza virus infection and trans-species transmission.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.