Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Equine MX2 is a restriction factor of equine infectious anemia virus (EIAV).

Virology - 1 Oct 2018

Meier Kristina, Jaguva Vasudevan Ananda Ayyappan, Zhang Zeli, Bähr Ariane, Kochs Georg, Häussinger Dieter, Münk Carsten

Abstract excerpt

Human myxovirus resistance protein B (hMXB) is a restriction factor of HIV-1 that also inhibits a variety of retroviruses. However, hMXB is not antiviral against equine infectious anemia virus (EIAV). We show here that equine MX2 (eMX2) potently restricts EIAV in vitro. Additionally, eMX2 inhibits HIV-1 and other lentiviruses, including murine leukemia virus. Previously, it was reported that hMXB repression is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV-1
Share to Genetic Vectors
Share to Guanosine Triphosphate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Horses

Share to Host-Pathogen Interactions

Share to Infectious Anemia Virus, Equine

Share to Lentivirus

Share to Myxovirus Resistance Proteins

Source

Identifiers

PMID: 30081309
DOI: 10.1016/j.virol.2018.07.024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Equine MX2 is a restriction factor of equine infectious anemia virus (EIAV).PMID 30081309Read ↗

Equine Mx1 Restricts Influenza A Virus Replication by Targeting at Distinct Site of its Nucleoprotein.Semantic proximity Read ↗

Host cell restriction factors of equine infectious anemia virusSemantic proximity Read ↗

Equine Tetherin Blocks Retrovirus Release and Its Activity Is Antagonized by Equine Infectious Anemia Virus Envelope ProteinSemantic proximity Read ↗

Equine Infectious Anemia Virus Resists the Antiretroviral Activity of Equine APOBEC3 Proteins through a Packaging-Independent MechanismSemantic proximity Read ↗

Human MxB Protein Is a Pan-herpesvirus Restriction Factor.Semantic proximity Read ↗

Diversity of interferon inducible Mx gene in horses and association of variations with susceptibility vis-à-vis resistance against equine influenza infection.Semantic proximity Read ↗

A Triple-Arginine Motif in the Amino-Terminal Domain and Oligomerization Are Required for HIV-1 Inhibition by Human MX2Semantic proximity Read ↗

The Interferon-Induced Mx2 Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication.Semantic proximity Read ↗

The S2 gene of equine infectious anemia virus is dispensable for viral replication in vitro.Semantic proximity Read ↗

Identification of functional domains of the IR2 protein of equine herpesvirus 1 required for inhibition of viral gene expression and replication.Semantic proximity Read ↗

Strain-Specific Antagonism of the Human H1N1 Influenza A Virus against Equine Tetherin.Semantic proximity Read ↗

Conserved arginine residues in the carboxyl terminus of the equine arteritis virus E protein may play a role in heparin binding but may not affect viral infectivity in equine endothelial cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.