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Article

Influenza A Virus Strains Differ in Sensitivity to the Antiviral Action of Mx-GTPase

17 Jan 2008

Abstract excerpt

Interferon-mediated host responses are of great importance for controlling influenza A virus infections. It is well established that the interferon-induced Mx proteins possess powerful antiviral activities toward most influenza viruses. Here we analyzed a range of influenza A virus strains for their sensitivities to murine Mx1 and human MxA proteins and found remarkable differences. Virus strains of avian origin...

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Identifiers

PMID: 18199636
DOI: 10.1128/jvi.01753-07

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