Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetics of paediatric acute myeloid leukaemia.

British journal of haematology - 1 Jan 2020

Jones Luke, McCarthy Peter, Bond Jonathan

Abstract excerpt

Comprehensive cataloguing of the acute myeloid leukaemia (AML) genome has revealed a high frequency of mutations and deletions in epigenetic factors that are frequently linked to treatment resistance and poor patient outcome. In this review, we discuss how the epigenetic mechanisms that underpin normal haematopoiesis are subverted in AML, and in particular how these processes are altered in childhood and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Child
Share to Drug Resistance, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Hematopoiesis

Share to Leukemia, Myeloid, Acute

Share to Mutation

Source

Identifiers

PMID: 31804725
DOI: 10.1111/bjh.16361

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetics of paediatric acute myeloid leukaemia.PMID 31804725Read ↗

Epigenetic Modifications in Pediatric Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Harnessing the potential of epigenetic therapies for childhood acute myeloid leukemia.Semantic proximity Read ↗

Epigenetic Modifications in Acute Myeloid Leukemia: Prognosis, Treatment, and HeterogeneitySemantic proximity Read ↗

Epigenetic alterations in acute myeloid leukemiasSemantic proximity Read ↗

Epigenetic dysregulation in acute myeloid leukemia.Semantic proximity Read ↗

Epigenetics in Hematological Malignancies.Semantic proximity Read ↗

Epigenetic regulators as promising therapeutic targets in acute myeloid leukemiaSemantic proximity Read ↗

Epigenetic Regulators in the Development, Maintenance, and Therapeutic Targeting of Acute Myeloid LeukemiaSemantic proximity Read ↗

Epigenetics in pediatric acute lymphoblastic leukemiaSemantic proximity Read ↗

Clinical developments in epigenetic-directed therapies in acute myeloid leukemiaSemantic proximity Read ↗

Genetics and epigenetics of pediatric leukemia in the era of precision medicineSemantic proximity Read ↗

Pediatric acute myeloid leukemia: biology and therapeutic implications of genomic variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.