Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Harnessing the potential of epigenetic therapies for childhood acute myeloid leukemia.

Experimental hematology - 1 Jul 2018

Newcombe Ashley A, Gibson Brenda E S, Keeshan Karen

Abstract excerpt

There is a desperate need for new and effective therapeutic approaches to acute myeloid leukemia (AML) in both children and adults. Epigenetic aberrations are common in adult AML, and many novel epigenetic compounds that may improve patient outcomes are in clinical development. Mutations in epigenetic regulators occur less frequently in AML in children than in adults. Investigating the potential benefits of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clinical Trials as Topic
Share to Combined Modality Therapy
Share to Gene Expression Regulation, Leukemic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Neoplasm

Share to Hematopoiesis

Share to Histone Code

Share to Histone Deacetylase Inhibitors

Share to Oncogene Proteins, Fusion

Source

Identifiers

PMID: 29608923
DOI: 10.1016/j.exphem.2018.03.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Harnessing the potential of epigenetic therapies for childhood acute myeloid leukemia.PMID 29608923Read ↗

Clinical developments in epigenetic-directed therapies in acute myeloid leukemiaSemantic proximity Read ↗

Molecular-Targeted Therapy of Pediatric Acute Myeloid Leukemia.Semantic proximity Read ↗

Epigenetics and approaches to targeted epigenetic therapy in acute myeloid leukemiaSemantic proximity Read ↗

Epigenetic regulators as promising therapeutic targets in acute myeloid leukemiaSemantic proximity Read ↗

Recent advances in the understanding and treatment of acute myeloid leukemiaSemantic proximity Read ↗

Recent Clinical Update of Acute Myeloid Leukemia: Focus on Epigenetic Therapies.Semantic proximity Read ↗

Epigenetic Regulators in the Development, Maintenance, and Therapeutic Targeting of Acute Myeloid LeukemiaSemantic proximity Read ↗

Epigenetics of paediatric acute myeloid leukaemia.Semantic proximity Read ↗

The evolving landscape of epigenetic target molecules and therapies in myeloid cancers: focus on acute myeloid leukemia and myeloproliferative neoplasmsSemantic proximity Read ↗

Epigenetic regulators and their impact on therapy in acute myeloid leukemiaSemantic proximity Read ↗

Epigenetics in Hematological Malignancies.Semantic proximity Read ↗

Epigenetic alterations in acute myeloid leukemiasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.