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Epigenetics in pediatric acute lymphoblastic leukemia

5 Sept 2017

Abstract excerpt

Acute lymphoblastic leukemia (ALL) is the most common malignancy in children. ALL arises from the malignant transformation of progenitor B- and T-cells in the bone marrow into leukemic cells, but the mechanisms underlying this transformation are not well understood. Recent technical advances and decreasing costs of methods for high-throughput DNA sequencing and SNP genotyping have stimulated systematic studies of...

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PMID: 28887175
DOI: 10.1016/j.semcancer.2017.09.001

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