Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vinculins interaction with talin is essential for mammary epithelial differentiation.

Scientific reports - 5 Dec 2019

Wang Pengbo, Wu Jian, Wood Amber, Jones Matthew, Pedley Robert, Li Weiping, Ross Robert S, Ballestrem Christoph, Gilmore Andrew P, Streuli Charles H

Abstract excerpt

Vinculin is an essential component of cell adhesion complexes, where it regulates the strength and stability of adhesions. Whilst the role of vinculin in cell motility is well established, it remains unclear how vinculin contributes to other aspects of tissue function. Here we examine the role of vinculin in mammary epithelial cell phenotype. In these cells, correct adhesion to the extracellular matrix is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion
Share to Cell Line, Transformed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cellular Microenvironment

Share to Mammary Glands, Animal

Share to Milk Proteins

Share to Primary Cell Culture

Share to Vinculin

Source

Open in PubMed Open full text

Identifiers

PMID: 31804547
DOI: 10.1038/s41598-019-54784-w
PMCID: PMC6895056

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vinculins interaction with talin is essential for mammary epithelial differentiation.PMID 31804547Read ↗

Expression of the cytoplasmic domain of E-cadherin induces precocious mammary epithelial alveolar formation and affects cell polarity and cell-matrix integrity.Semantic proximity Read ↗

Vinculin organises apical Transcellular Actin Fibres to coordinate collective migrationSemantic proximity Read ↗

Myoepithelial cell differentiation in the developing mammary gland: progressive acquisition of smooth muscle phenotype.Semantic proximity Read ↗

Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development.Semantic proximity Read ↗

Vinculin regulates the recruitment and release of core focal adhesion proteins in a force-dependent manner.Semantic proximity Read ↗

Defining functional interactions during biogenesis of epithelial junctions.Semantic proximity Read ↗

Signalling in extracellular-matrix-mediated control of epithelial cell phenotype.Semantic proximity Read ↗

The mammary myoepithelial cellSemantic proximity Read ↗

Two Distinct Integrin-Mediated Mechanisms Contribute to Apical Lumen Formation in Epithelial CellsSemantic proximity Read ↗

Control of normal mammary epithelial phenotype by integrins.Semantic proximity Read ↗

CLCA2 Interactor EVA1 Is Required for Mammary Epithelial Cell DifferentiationSemantic proximity Read ↗

The Integrin-Mediated ILK-Parvin-αPix Signaling Axis Controls Differentiation in Mammary Epithelial Cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.