Article
Signalling in extracellular-matrix-mediated control of epithelial cell phenotype.
Biochemical Society transactions - 1 Aug 1995
Edwards G, Streuli C
Abstract excerpt
Interactions with an appropriate ECM are crucial for normal cell behaviour. The basement membrane contributes to both the tissue-specific lactational function and survival of mammary epithelial cells, possibly through a similar beta 1-integrin-dependent mechanism. Of current interest is whether the downstream intracellular signals diverge, with milk expression regulated through cell shape and the Jak-Stat pathway...
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