Cross-subunit catalysis and a new phenomenon of recessive resurrection in Escherichia coli RNase E.

Abstract excerpt

RNase E is a 472-kDa homo-tetrameric essential endoribonuclease involved in RNA processing and turnover in Escherichia coli. In its N-terminal half (NTH) is the catalytic active site, as also a substrate 5'-sensor pocket that renders enzyme activity maximal on 5'-monophosphorylated RNAs. The protein's non-catalytic C-terminal half (CTH) harbours RNA-binding motifs and serves as scaffold for a multiprotein...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Catalysis
• Share to Catalytic Domain
• Share to Endoribonucleases