Article
Genetic uncoupling of the dsRNA-binding and RNA cleavage activities of the Escherichia coli endoribonuclease RNase III--the effect of dsRNA binding on gene expression.
Molecular microbiology - 1 May 1998
Dasgupta S, Fernandez L, Kameyama L, Inada T, Nakamura Y, Pappas A, Court D L
Abstract excerpt
RNase III, a double-stranded RNA-specific endonuclease, is proposed to be one of Escherichia coli's global regulators because of its ability to affect the expression of a large number of unrelated genes by influencing post-transcriptional control of mRNA stability or mRNA translational efficiency...
Topics
- Alleles
- Endoribonucleases
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression Regulation, Bacterial
- Operon
- Phenotype
- Plasmids
- Point Mutation
- Protein Binding
- RNA, Bacterial
- RNA, Double-Stranded
- Recombinant Fusion Proteins
- Ribonuclease III