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Article

Substrate-dependent effects of quaternary structure on RNase E activity.

Genes & development - 1 Feb 2021

Moore Christopher J, Go Hayoung, Shin Eunkyoung, Ha Hye-Jeong, Song Saemee, Ha Nam-Chul, Kim Yong-Hak, Cohen Stanley N, Lee Kangseok

Abstract excerpt

RNase E is an essential, multifunctional ribonuclease encoded in E. coli by the rne gene. Structural analysis indicates that the ribonucleolytic activity of this enzyme is conferred by rne-encoded polypeptide chains that (1) dimerize to form a catalytic site at the protein-protein interface, and (2) multimerize further to generate a tetrameric quaternary structure consisting of two dimerized Rne-peptide chains....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33446571
DOI: 10.1101/gad.335828.119
PMCID: PMC7849360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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