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Article

Tumor propagating cells: drivers of tumor plasticity, heterogeneity, and recurrence.

Oncogene - 1 Mar 2020

Vessoni Alexandre Teixeira, Filippi-Chiela Eduardo Cremonese, Lenz Guido, Batista Luis Francisco Zirnberger

Abstract excerpt

Tumorigenesis is associated with the development of a highly variable pattern of cellular diversity, consequence of genetic and epigenetic diversification, followed by clonal selection and expansion. This process is shaped by the microenvironment and leads to intratumoral heterogeneity, which is characterized by differences between cancer cells in terms of gene expression, phenotypic markers, growth dynamics, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31801972
DOI: 10.1038/s41388-019-1128-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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