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Article

Cancer cell plasticity: Impact on tumor progression and therapy response.

Seminars in cancer biology - 1 Dec 2018

da Silva-Diz Victoria, Lorenzo-Sanz Laura, Bernat-Peguera Adrià, Lopez-Cerda Marta, Muñoz Purificación

Abstract excerpt

Most tumors exhibit intra-tumor heterogeneity, which is associated with disease progression and an impaired response to therapy. Cancer cell plasticity has been proposed as being an important mechanism that, along with genetic and epigenetic alterations, promotes cancer cell diversity and contributes to intra-tumor heterogeneity. Plasticity endows cancer cells with the capacity to shift dynamically between a...

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Identifiers

PMID: 30130663
DOI: 10.1016/j.semcancer.2018.08.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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