Article
Association of HLA-G 3'UTR 14-bp Ins/Del polymorphism with breast cancer among South Indian women.
Journal of clinical pathology - 1 Aug 2020
Kadiam Sony, Ramasamy Thirunavukkarasu, Ramakrishnan Revathi, Mariakuttikan Jayalakshmi
Abstract excerpt
AIM: Human leucocyte antigen-G (HLA-G) and tumour necrosis factor-alpha (TNF-α) are potent immune mediators implicated in the pathogenesis of breast cancer. The polymorphisms in the 3' untranslated region (3'UTR) of HLA-G and promoter region of TNF-α are well known to influence their expression levels and may consequently contribute to varied disease predisposition. Therefore, in the present study, we explored...
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