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Article

Role of ethnic variations in TNF-α and TNF-β polymorphisms and risk of breast cancer in India.

Breast cancer research and treatment - 1 Apr 2011

Pooja Singh, Francis Amirtharaj, Bid Hemant Kumar, Kumar Sandeep, Rajender Singh, Ramalingam K, Thangaraj Kumarasamy, Konwar Rituraj

Abstract excerpt

TNF-α and -β, the multi-functional pro-inflammatory cytokines, are known to play important roles in both tumor progression and destruction based on their concentrations. Growth factors and various stimuli such as cytokines regulate proliferation of the breast epithelial cells. Therefore, the polymorphisms in the genes encoding these signaling molecules could affect the risk of breast cancer. We have investigated...

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PMID: 20878356
DOI: 10.1007/s10549-010-1175-6

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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