Article
Genetic Polymorphism in TNF-α-308 G/A and TNF-β +252 A/G, as Prognostic Biomarker in Breast Cancer Patients among Indian Population.
Asian Pacific journal of cancer prevention : APJCP - 1 Feb 2020
Ahmad Mohammad Margoob, Parveen Farah, Akhter Naseem, Siddiqui Jamshaid Ahmad, Shukla Nootan Kumar, Husain Syed Akhtar
Abstract excerpt
BACKGROUND: Cytokines are the key regulator molecules that modulate immune response. Tumor necrosis factor (TNF- α-308 G/A and TNF-β +252 A/G ) are inflammatory cytokine that control the progression of several types of cancer. They play a vital role in both tumor progression and destruction based on their concentrations. The role of TNF-α-308 G/A and TNF-β +252 A/G gene polymorphism in the etiology of breast...
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