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Article

Embryonic Cells Redistribute SUMO1 upon Forced SUMO1 Overexpression.

mBio - 3 Dec 2019

Lee Andreia, Zhu Yiping, Sabo Yosef, Goff Stephen P

Abstract excerpt

Conjugation of small ubiquitin-like modifiers (SUMOs) to substrate proteins is a posttranslational protein modification that affects a diverse range of physiological processes. Global inhibition of SUMO conjugation in mice results in embryonic lethality, reflecting the importance of the SUMO pathways for embryonic development. Here, we demonstrated that SUMO1 overexpression was not well tolerated in murine...

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Identifiers

PMID: 31796536
DOI: 10.1128/mBio.01856-19
PMCID: PMC6890988

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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