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Article

SUMOylation and deSUMOylation at a glance

19 Nov 2009

Abstract excerpt

Small ubiquitin-related modifiers (SUMOs) are ubiquitin-like polypeptides that become covalently conjugated to cellular proteins in a manner similar to ubiquitylation (Johnson, 2004). More than 1000 proteins have been identified as potential SUMO-conjugation (SUMOylation) targets (Hochstrasser, 2009), and this pathway has been implicated in controlling many aspects of cell physiology, including cell-cycle...

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PMID: 19923268
DOI: 10.1242/jcs.050542

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