Article

Alternative splicing of the SUMO transcripts contributes to the regulation of the cellular SUMOylation system and produces messages coding for protein isoforms functionally distinct from the prototypical SUMO proteins

2022-09-09

Abstract excerpt

Substantial increases in the conjugation of the main human SUMO paralogs, SUMO1, SUMO2, and SUMO3, are observed upon exposure to different cellular stressors, and such increases are considered important to facilitate cell survival to stress. Despite their critical cellular role, little is known about how the levels of the SUMO modifiers are regulated in the cell, particularly as it relates to the changes observed...

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Identifiers and source

Literature Corpus work: f21ac7d4-4e11-55b0-aa6d-220085306c2b
DOI: 10.21203/rs.3.rs-2011524/v1

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