Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A differential requirement for SUMOylation in proliferating and non-proliferating cells during Drosophila development.

Development (Cambridge, England) - 1 Aug 2012

Kanakousaki Kiriaki, Gibson Matthew C

Abstract excerpt

SUMOylation is a highly conserved post-translational modification shown to modulate target protein activity in a wide variety of cellular processes. Although the requirement for SUMO modification of specific substrates has received significant attention in vivo and in vitro, the developmental requirements for SUMOylation at the cell and tissue level remain poorly understood. Here, we show that in Drosophila...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Homeostasis
Share to Imaginal Discs
Share to Ligases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitosis

Share to Photoreceptor Cells, Invertebrate

Share to Salivary Glands

Share to Small Ubiquitin-Related Modifier Proteins

Share to Ubiquitin-Activating Enzymes

Source

Identifiers

PMID: 22745316
DOI: 10.1242/dev.082974

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A differential requirement for SUMOylation in proliferating and non-proliferating cells during Drosophila development.PMID 22745316Read ↗

Sumoylation in Development and Differentiation.Semantic proximity Read ↗

Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development.Semantic proximity Read ↗

A Deficiency in SUMOylation Activity Disrupts Multiple Pathways Leading to Neural Tube and Heart Defects in <i>Xenopus</i> EmbryosSemantic proximity Read ↗

The SUMO system in Caenorhabditis elegans development.Semantic proximity Read ↗

Pervasive SUMOylation of heterochromatin and piRNA pathway proteinsSemantic proximity Read ↗

Uncovering SUMOylation Dynamics during Cell-Cycle Progression Reveals FoxM1 as a Key Mitotic SUMO Target ProteinSemantic proximity Read ↗

The SUMO activating enzyme subunit, SAE2, contributes SUMO protein bias for mitotic fidelitySemantic proximity Read ↗

Analysis of Small Ubiquitin-Like Modifier (SUMO) Targets Reflects the Essential Nature of Protein SUMOylation and Provides Insight to Elucidate the Role of SUMO in Plant DevelopmentSemantic proximity Read ↗

SUMOylation and deSUMOylation at a glanceSemantic proximity Read ↗

Modification of Drosophila p53 by SUMO modulates its transactivation and pro-apoptotic functions.Semantic proximity Read ↗

Senp1 is essential for desumoylating Sumo1-modified proteins but dispensable for Sumo2 and Sumo3 deconjugation in the mouse embryo.Semantic proximity Read ↗

Embryonic Cells Redistribute SUMO1 upon Forced SUMO1 Overexpression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.