Article
Relationship of prolonged acoustic startle latency to diagnosis and biotype in the bipolar-schizophrenia network on intermediate phenotypes (B-SNIP) cohort.
Schizophrenia research - 1 Feb 2020
Massa Nicholas, Owens Andrew V, Harmon Wesley, Bhattacharya Arpita, Ivleva Elena I, Keedy Sarah, Sweeney John A, Pearlson Godfrey D, Keshavan Matcheri S, Tamminga Carol A, Clementz Brett A, Duncan Erica
Abstract excerpt
BACKGROUND: Latency of the acoustic startle reflex is the time from presentation of the startling stimulus until the response and provides an index of neural processing speed. Latency is prolonged in schizophrenia, is 90% heritable, and predicts conversion to schizophrenia in a high-risk population. The Bipolar-Schizophrenia Network for Intermediate Phenotypes (B-SNIP) consortium investigates neurobiological...
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